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Tarkoititko ayahuasca ja psykoottisuudessanne

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Kyllä.

Potential benefits of Ayahuasca

Many people who have taken Ayahuasca claim that the experience led to positive, long-term, life-altering changes. This may be due to the effects of Ayahuasca on the neurological system.

Recent research has shown that Ayahuasca may benefit health — particularly brain health — in a number of ways.

May benefit brain health

The main active ingredients in Ayahuasca — DMT and -carbolines — have been shown to exhibit neuroprotective and neurorestorative qualities in some studies.

DMT activates the sigma-1 receptor (Sig-1R), a protein that blocks neurodegeneration and regulates the production of antioxidant compounds that help protect your brain cells (5Trusted Source).

A test-tube study indicated that DMT protected human brain cells from damage caused by lack of oxygen and increased cell survival (5Trusted Source).

Harimine, the main -carboline in Ayahuasca, has been found to have anti-inflammatory, neuroprotective, and memory-boosting effects in test-tube and animal studies (6Trusted Source, 7Trusted Source).

It has also been observed to increase levels of brain-derived neurotrophic factor (BDNF), a protein that plays an important role in nerve cell growth and promotes nerve cell survival (6Trusted Source).

Additionally, a test-tube study demonstrated that exposure to harmine increased the growth of human neural progenitor cells by over 70% in 4 days. These cells generate the growth of new neural cells in your brain (8Trusted Source).

May improve psychological well-being

Research has shown that taking Ayahuasca may increase the mindfulness capacity of your brain and improve your overall psychological well-being.

A study in 20 people indicated that consuming Ayahuasca once weekly for 4 weeks was as effective as an 8-week mindfulness program at increasing acceptance — a component of mindfulness that plays a fundamental role in psychological health (9Trusted Source).

Other studies have found similar results, noting that Ayahuasca may improve mindfulness, mood, and emotional regulation (10Trusted Source).

A study in 57 people demonstrated that ratings of depression and stress were significantly decreased immediately after the participants consumed Ayahuasca. These effects were still significant 4 weeks following the Ayahuasca consumption (11Trusted Source).

They’re mostly attributed to the DMT and -carbolines in Ayahuasca (12Trusted Source).

May help treat addiction, anxiety, treatment-resistant depression, and PTSD

Some research suggests that Ayahuasca may benefit those with depression, post-traumatic stress disorder (PTSD), and addiction disorders.

A study in 29 people with treatment-resistant depression showed that a single dose of Ayahuasca led to significant improvements in depression severity compared with a placebo. Other studies report rapid antidepressant effects of Ayahuasca as well (13Trusted Source, 14Trusted Source).

Additionally, a review of six studies concluded that Ayahuasca showed beneficial effects in treating depression, anxiety, mood disorders, and drug dependence (15Trusted Source).

Several older studies have focused on the effects of Ayahuasca on addiction disorders, including addictions to crack cocaine, alcohol, and nicotine — with promising results (16Trusted Source).

In one 2013 study, 12 people with severe psychological and behavioral issues related to substance abuse participated in a 4-day treatment program that included 2 Ayahuasca ceremonies (17Trusted Source).

At a 6-month follow up, they demonstrated significant improvements in mindfulness, hopefulness, empowerment, and overall quality of life. Plus, self-reported use of tobacco, cocaine, and alcohol significantly declined (17Trusted Source).

Researchers hypothesize that Ayahuasca may help those with PTSD as well, though more research in this area is needed (18Trusted Source).

https://www.healthline.com/nutrition/ayahuasca#benefits