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There was no evidence that infection during pregnancy was associated with adverse consequences for the infant.
Exposure to RS virus in the first two trimesters, but not the third, was associated with high colostral IgA antibody levels that were maintained in the milk throughout the first 7 weeks of lactation. There was a significant correlation between colostral and maternal nasal IgA antibody levels at delivery. Levels of blood or colostral lymphocyte transformation responses at delivery were unaffected by exposure to RS virus in pregnancy.
These observations upon natural infection suggest that vaccination during pregnancy is likely to achieve only marginal effects upon serum antibody levels but boost maternal mammary/nucosal immunity.
Kommentit (3)
Vierailija:
There was no evidence that infection during pregnancy was associated with adverse consequences for the infant.
Exposure to RS virus in the first two trimesters, but not the third, was associated with high colostral IgA antibody levels that were maintained in the milk throughout the first 7 weeks of lactation. There was a significant correlation between colostral and maternal nasal IgA antibody levels at delivery. Levels of blood or colostral lymphocyte transformation responses at delivery were unaffected by exposure to RS virus in pregnancy.
These observations upon natural infection suggest that vaccination during pregnancy is likely to achieve only marginal effects upon serum antibody levels but boost maternal mammary/nucosal immunity.
Ei loytynyt todisteita sille, etta aidin raskaudenaikainen sairastuminen aiheuttaisi vaaraa vauvalle.
Vierailija:
There was no evidence that infection during pregnancy was associated with adverse consequences for the infant.
Ei ole näyttöä siitä, että raskauden aikainen infektio aiheuttaisi haittaa vastasyntyneelle.
Exposure to RS virus in the first two trimesters, but not the third, was associated with high colostral IgA antibody levels that were maintained in the milk throughout the first 7 weeks of lactation.
Altistumiseen RS virukselle raskauden kahden ekan kolmanneksen, mutta ei vipan kolmanneksen, aikana liittyi korkeat ensimaidon (kolostrum) IgA-tyypin vasta-ainepitoisuudet jotka pysyivät ainakin 7 vk imetyksen ajan.
There was a significant correlation between colostral and maternal nasal IgA antibody levels at delivery. Levels of blood or colostral lymphocyte transformation responses at delivery were unaffected by exposure to RS virus in pregnancy.
Nenän (limakalvojen) ja kolostrumin vasta-ainepitoisuudet korreloivat. valkosoluvasteisiin RS-virusaltistus ei vaikuttanut.
These observations upon natural infection suggest that vaccination during pregnancy is likely to achieve only marginal effects upon serum antibody levels but boost maternal mammary/nucosal immunity.
Nämä havainnot luonnollisesta infektiosta viittaavat siihen, että rokotus (RS-virusta vastaan) raskauden aikana vaikuttaisi vain hiukan veren seerumin vasta-ainetasoihin mutta parantaisi äidin rintarauhasen ja limakalvojen immuniteettia eli puolustusjärjestelmää.
RS:n vasta-aineita.