raskaus ja doximed

Tetrasykliinit ovat teratogeenisiä ja voivat aiheuttaa sikiöille ainakin hampaiden värjäytymistä (mikä ei lähde pois). 18. raskausviikon jälkeen niitä voi syödä. Mitään vakavampaa tietääkseni niistä ei tule.

Niin ja ilmeisesti sikiövaiheessa värjäytyminen koskee vain maitohampaita. Täällä lisää tietoa ja myös kuva, miltä nuo värjäytyneet hampaat näyttää. http://www.oralanswers.com/tetracycline-tooth-staining-cause-treatment-prevention/

Doxycycline hyclate should not be used in patients who are hypersensitive to doxycycline or any other drug in the tetracycline class.

THE USE OF DRUGS OF THE TETRACYCLINE CLASS DURING TOOTH DEVELOPMENT (LAST HALF OF PREGNANCY, INFANCY, AND CHILDHOOD TO THE AGE OF 8 YEARS) MAY CAUSE PERMANENT DISCOLORATION OF THE TEETH. This adverse reaction is more common during long-term use of the drugs, but has been observed following repeated short-term courses. Enamel hypoplasia has also been reported. TETRACYCLINE DRUGS, THEREFORE, SHOULD NOT BE USED IN THIS AGE GROUP, OR IN PREGNANT WOMEN, UNLESS OTHER DRUGS ARE NOT LIKELY TO BE EFFECTIVE OR ARE CONTRAINDICATED.

All tetracyclines form a stable calcium complex in any bone forming tissue. A decrease in fibula growth rate has been observed in premature infants given oral tetracyclines in doses of 25 mg/kg every 6 hours. This reaction was shown to be reversible when the drug was discontinued.

Doxycycline can cause fetal harm when administered to a pregnant woman. Results of animal studies indicate that tetracyclines cross the placenta, are found in fetal tissues, and can have toxic effects on the developing fetus (often related to retardation of skeletal development). Evidence of embryotoxicity has also been noted in animals treated early in pregnancy. If any tetracyclines are used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus.

Voi kun en osaa englantia..